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Praeruptorin A

CAS No. 73069-27-9

Praeruptorin A( —— )

Catalog No. M19050 CAS No. 73069-27-9

Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	116	In Stock
10MG	197	In Stock
25MG	295	In Stock
50MG	446	In Stock
100MG	620	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Praeruptorin A
Note

Research use only, not for human use.
Brief Description

Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.
Description

Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

CAM
Research Area

Others-Field
Indication

——

Chemical Information

CAS Number

73069-27-9
Formula Weight

386.4
Molecular Formula

C21H22O7
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 33.33 mg/mL (86.26 mM)
SMILES

C/C=C(/C)\C(=O)O[C@H]1[C@H](c2c(ccc3c2oc(=O)cc3)OC1(C)C)OC(=O)C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Xu Z1, Wang X, Dai Y, Kong L, et al..Chem Biol Interact. 2010 Jul 30;186(2):239-46.

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